Author：Verdini,Giulio;Bina,Olivia;Chiles,Prue;Guerrieri,Pilar Maria;Mace,Alan;Nolf,Christian;Occhialini,Etra Connie;Pola,Anna Paola;Raffa,Paola

Abstract:This chapter intends to be both scientifically sound and narratively engaging, given the richness of the work done in Gagliato as experienced by the authors. As a matter of fact, besides the research done remotely, the authors gathered in Gagliato in July 2017 for a one-week participatory design workshop, getting to know the local context, talking with local people, materialising the focus groups implemented on site in future visions of sustainable development. Gagliato is a hilly town located in the province of Catanzaro in Calabria, overlooking the Ionian Sea. The chapter introduces a theoretical section regarding current debates on transdisciplinary research and the reason why Gagliato has been considered a suitable case to test it. The enabling conditions and potential barriers to achieve meaningful transdisciplinary outcomes and consequently tangible positive urban transformation of the experience of Gagliato will be discussed in relationship to the various phases of the project.

Author：Poshan Yu, Samuel Kwok and Zhongyue Jiang

Abstract:This chapter aims to investigate the impacts of COVID-19 in China's education sector. It will capture the dynamics of the interlinked changing relationships between the availability and use of education technology (EdTech) and the demand for online learning among various stakeholders in the Chinese education market. In addition, this chapter examines whether and how these relationships enhance operational efficiency via transforming the current business models in the sector, in particular due to the COVID-19 pandemic. By analyzing the current practices of the sector, this chapter will critically discuss the challenges and opportunities for technology in education and how these changes in turn drive stakeholders (including students, educators, and regulators) to respond and engage with each other, and how these stakeholder engagements impact the sustainable development of delivery modes, such as digital education and remote learning by using EdTech strategies in the sector.

Author：Golightly,Lewis;Chang,Victor;Xu,Qianwen Ariel

Abstract:The increase and advancements of network technology play a significant role in the lives of us. This is through homes, businesses and people in a professional and social capacity. The way we use technology in everyday life aids the friendships, achievements and entertainment parts of our day to day life. This makes the fundamental device in the network important to every one of us for conducting our day to day life–that device is the router. Much like a fridge or cooker would have in the 1950 s, the router is considered as a critical device in the home and business setting. This paper aims to demonstrate a penetration test documentation of a standard home or small business Router–TP-Link WR940N by using the operating system Kali Linux 2019/2020. The main aim of the paper is to show the extent of what someone can do and the lengths someone can go from essentially sitting outside your house in a car with a raspberry pi, a Wi-Fi adapter, a seven-inch screen, and a travel battery for power.

Author：Toke,David;Chen,Geoffrey Chun Fung;Froggatt,Antony;Connolly,Richard

Abstract:This book studies the extent to which nuclear safety issues have contributed towards the stagnation of nuclear power development around the world, and accounts for differences in safety regulations in different countries. In order to understand why nuclear development has not met widespread expectations, this book focusses on six key countries with active nuclear power programmes: the USA, China, France, South Korea, the UK, and Russia. The authors integrate cultural theory and theory of regulation, and examine the links between pressures of cultural bias on regulatory outcomes and political pressures which have led to increased safety requirements and subsequent economic costs. They discover that although nuclear safety is an important upward driver of costs in the nuclear power industry, this is influenced by the inherent need to control potentially dangerous reactions rather than stricter nuclear safety standards. The findings reveal that differences in the strictness of nuclear safety regulations between different countries can be understood by understanding differences in cultural contexts and the changes in this over time. This book will be of great interest to students, scholars, and policymakers working on energy policy and regulation, environmental politics and policy, and environment and sustainability more generally.

Author：Goodman,David S.G.

Author：Penn Tsz Ting Ip, Yu Zhang, Xi Liu

Abstract:《海上凡花：上海工人新村妇女日常生活》是“城市化、性别与南半球——改造知识网络研究项目上海团队(GenUrb)”的项目研究成果，包括对上海工人新村的六位女性、三对基层母女的口述历史访谈，以及为期四周线上线下混合进行的日记工作坊，通过参与式田野观察，探讨社会主义建设下的城市发展与家庭社区视角的性别议题。

Author：Liu, X., Wang, X., & Hu, Y.

Abstract:This original book is a unique and original study on how, in the past decade, Chinese state-owned enterprises (SOEs) have achieved technological innovation in the large infrastructure sector. It reveals a ‘new world’ of Chinese innovations, showing that SOEs are willing to innovate and more than capable of doing so. Based on findings from first-hand data and years of in-depth observations, this book shows how the innovation ecosystem perspective incentivizes and facilitates Chinese SOEs’ innovation and highlights entrepreneurial role of the government.

Author：Xu,Qingru;Chen,Kunqi;Meng,Jia

Abstract:N6-Methyladenosine (m6A) is the most prevalent posttranscriptional modification in eukaryotes and plays a pivotal role in various biological processes, such as splicing, RNA degradation, and RNA–protein interaction. Accurately identification of the location of m6A is essential for related downstream studies. In this chapter, we introduce a prediction framework WHISTLE, which enables us to acquire so far the most accurate map of the transcriptome-wide human m6A RNA-methylation sites (with an average AUC: 0.948 and 0.880 under the full transcript or mature messenger RNA models, respectively, when tested on independent datasets). Besides, each individual m6A site was also functionally annotated according to the “guilt-by-association” principle by integrating RNA methylation data, gene expression data and protein–protein interaction data. A web server was constructed for conveniently querying the predicted RNA methylation sites and their putative biological functions. The website supports the query by genes, by GO function, table view, and the download of all the functionally annotated map of predicted map of human m6A epitranscriptome. The WHISTLE web server is freely available at: www.xjtlu.edu.cn/biologicalsciences/whistle and http://whistle-epitranscriptome.com.

Author：Liu,Hui;Ma,Jiani;Meng,Jia;Zhang,Lin

Abstract:N6-methyladenosine (m6A) is the most prevalent posttranscriptional modification in eukaryotes and plays a pivotal role in various biological processes. A knowledge base with the systematic collection and curation of context specific transcriptome-wide methylations is critical for elucidating their biological functions as well as for developing bioinformatics tools. In this chapter, we present a comprehensive platform MeT-DB V2.0 for elucidating context-specific functions of N6-methyl-adenosine methyltranscriptome. Met-DB V2.0 database contains context specific m6A peaks and single-base sites predicted from 185 samples for 7 species from 26 independent studies. Moreover, it is also integrated with a new database for targets of m6A readers, erasers and writers and expanded with more collections of functional data. The Met-DB V2.0 web interface and genome browser provide more friendly, powerful, and informative ways to query and visualize the data. More importantly, MeT-DB V2.0 offers for the first time a series of tools specifically designed for understanding m6A functions. The MeT-DB V2.0 web server is freely available at: http://compgenomics.utsa.edu/MeTDB and www.xjtlu.edu.cn/metdb2.

Author：Pan,Peng;Song,Pengfei;Dong,Xianke;Zhang,Weize;Sun,Yu;Liu,Xinyu

Abstract:Micromanipulation and immobilization of single cells and small organisms (e.g., Caenorhabditis elegans and Drosophila larva) are important experimental techniques in biological and biomedical research. Because of the micrometer sizes and highly fragile structures of cells and small organisms, conventional manipulation and immobilization techniques are not accurate and/or efficient enough to meet certain demanding needs in cellular and organismal studies. To this end, different types of microfluidic device have been developed to improve the accuracy, efficiency, and consistency of cell/organism immobilization and manipulation, which enables high-throughput single cell/organism analysis. In this chapter, we will discuss three microfluidic devices we previously developed for immobilization and robotic micromanipulation of single cells and small organisms. In closing, a conclusion and outlook into future trends is also provided.